Some FDA case reports that found dogs diagnosed with DCM consuming grain-free diets also had low concentrations of plasma and/or whole blood taurine. While there is a known association between low taurine status and DCM, there is little clinical evidence on the relationship of commercial grain-free diets and taurine status in healthy large-breed dogs.
High-protein, grain-free extruded dog diets are increasing in popularity, but few have compared the digestibility of these diets to others containing different ingredients or nutrient concentrations.